Automatic Lipid Nanoparticle Synthesizer

Automatic Lipid Nanoparticle Synthesizer

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Automatic Lipid Nanoparticle Synthesizer

FlowNano-S5 is a fully automatic lipid nanoparticle synthesizer built upon microfluidic chip technology. The instrument adopts a patented baffle-type microfluidic chip design, integrated with tube-in-tube rapid dialysis and in-line particle size detection, enabling high-efficiency, automated and controllable synthesis of lipid nanoparticle pharmaceuticals. In addition, the innovative chip architecture lays a solid and reliable foundation for production scale-up.

Features

  • Unique baffle-type microchannel chip design enables seamless transition from lab-scale nanoparticle synthesis process verification to scaled-up production.

  • Independent automatic flushing mode ensures reusability of the microfluidic chip. 

  • Quick plug-in syringe mounting structure minimizes sample loss to nearly zero.

  • Sterile single-use syringes and tubing drastically reduce cross-contamination within fluidic pathways.

  • Built-in in-situ nanoparticle detector for real-time monitoring of synthesized nanoparticle size and PDI distribution.
  • Reserved in-line dialysis interface allows continuous execution of synthesis and dialysis processes.

Specifications

Item Specifications
Preparation Volume 0.3–5 mL
Maximum Withstand Pressure 5 bar
Flow Rate Range 0.5–5 mL/min
Channel Dimension 50 μm
Particle Diameter Range 40–500 nm
Particle Monodispersity PDI<0.2*

 

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